Cheapest return flights from Madrid (MAD) to Panama City (PTY)

Cheapest month: January 2027, from $ 603. Book in one tap, or open a month for every date.

All destinations from Madrid (MAD)

One-wayReturn

  • October 2026

    12 Oct – 25 Feb 2027 136 nights
    $ 1,209 return
    Direct Air Europa
    Price seen 8 Oct
    October dates

  • November 2026

    22 Nov – 20 Jan 2027 59 nights
    $ 842 return
    Turkish Airlines
    Price seen 9 Oct
    November dates

  • January 2027

    22–31 Jan 2027 9 nights
    $ 603 return Cheapest month
    Avianca
    Price seen 9 Oct
    January dates

  • May 2027

    1–16 May 2027 15 nights
    $ 649 return
    Avianca
    Price seen 9 Oct
    May dates

  • June 2027

    20 Jun – 6 Jul 2027 16 nights
    $ 603 return
    Avianca
    Price seen 8 Oct
    June dates
Powered by

Deals for one-way flights from Madrid to Panama City.

Book a cheap hotel in Panama City

Cheap car rent in Tocumen Intl

Updated Oct 9, 2026.

About these fares

These results come from our latest search across airlines for your currency. Prices change quickly and are not locked until you complete booking—always confirm the total and fare rules on the partner site.

Feel free to contact us with any feedback or request another flight research.